Scientists are still using decades-old methods for extracting DNA and RNA from biological samples. Unfortunately, those approaches often involve laborious workflows, low yields, and variable quality of resulting nucleic acid. Purigen’s isotachophoresis technology, on the other hand, allows scientists to purify their samples with a simple, reliable, and automated method. Instead of binding DNA or RNA to a substrate and then ripping it off — often causing damage in the process — our gentle technique relies on a simple charge-based separation in solution. No binding, no harsh chemicals — just pure nucleic acids, ready for your next experiment.
In this video, Purigen CSO, Klint Rose walks viewers through how isotachophoresis works on the Ionic® Purification System, with a look back to its original conception at Stanford University and its development by four people working out of a small lab in Pleasanton, California.
Klint Rose, Ph.D., Purigen Biosystems
When exposed to an electric charge, it turns out that DNA and RNA move faster than the other elements present in a sample. Purigen's approach capitalizes on the ability of nucleic acids to outrun the impurities, so we capture only the good stuff for downstream analysis. The whole automated process takes just an hour and runs on its own with the push of a button.
Purigen’s technology works on even the most complex samples, so it can safely be used with precious or low-volume samples.