Pure DNA and RNA Extraction | Purigen Biosystems

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Simple Charge-based DNA and RNA Extraction

The Next-Gen Sample Prep System

The revolutionary Ionic® Purification System requires no binding, no stripping, and no washing from fixed surfaces for much higher yields and higher quality nucleic acid.
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No Beads, No Columns, No Surface-binding

Simple, Automated, Charge-based DNA and RNA Extraction

Isotachophoresis separates and concentrates charged molecules in solution solely based on their electrophoretic mobility for pure DNA, RNA, and miRNA extraction.
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Ionic® Tissue to Pure DNA

Improved Yields from Fresh Frozen Tissue

Simple, automated extraction of DNA from a variety of tissue types with less hands-on time than conventional bead- and column-based methods.
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Pure, Native, Intact DNA, RNA and miRNA: Biological samples are gently lysed without the use of chaotropic salts. Nucleic acids are not denatured or dehydrated.

Higher Amplifiable Yields and Better Data: Extract up to 50% more DNA from cultured cells, and 3.5x more DNA and 2x more RNA from FFPE samples versus traditional column-based methods.

No Beads, No Columns, No Surface-binding: Nucleic acids are purified solely based on electrophoretic mobility. Elimination of binding, washing, and stripping reduces sample loss and contamination.

No Risk Downstream: Purification is not biased toward nucleic acids of a certain length or GC content.

Superior Workflow for FFPE: Extraction of RNA, DNA, and miRNA from FFPE scrolls or slides requires less than
3 minutes of hands-on time per sample (lysis included). No chemical deparaffinization is required.

Automated Nucleic Acid Purification: Nucleic acids are automatically separated and concentrated from sample lysate on the Ionic Purification System in
~60 minutes.

VIDEO: Transforming Cancer Genomics with Purigen's Next-Gen Sample Prep - with CEO, Barney Saunders - WATCH VIDEO

See the Ionic Purification System in Action

The application of ITP to purify and quantify nucleic acids from complex biological samples was pioneered by Purigen co-founder and Stanford University Professor, Juan G. Santiago. The Ionic Purification System is compatible with a range of samples including cells and FFPE to help researchers, scientists, pathologists, and oncologists find the best method for DNA and RNA extraction.