DNA Extraction - Pure and Simple | Purigen Biosystems

White Paper

Isotachophoresis Improves Nucleic Acid Extraction

Download our new white paper and learn how the Ionic system is transforming FFPE sample analysis.
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Proof-of-Performance (POP) Study

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We invite you try Purigen and see the difference. Our POP study is available to any researcher wanting to compare their results to the Purigen Ionic System.
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Purigen Biosystems

Nucleic Acid Purification – Pure and Simple™

The Ionic™ Purification System isolates pure, native, nucleic acid without the use of harsh lysis steps or chaotropic salts.
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No beads, columns, or surface binding

Simplified Charge-based DNA Extraction

Isotachophoresis (ITP) separates and concentrates charged molecules in solution solely based on their electrophoretic mobility.
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Purigen Ionic Kits

Simplify Your Purification Workflows

Purigen protocols, fluidics chips, and reagents maximize nucleic acid yield and quality with fewer manual steps.
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WHITE PAPER - Isotachophoresis Improves Nucleic Acid Extraction and Purification from FFPE - DOWNLOAD TODAY!

Pure, Native, Nucleic Acid: Biological samples are gently lysed without the use of chaotropic salts. Nucleic acids are not dehydrated or denatured.

Higher Amplifiable Yields: Extract up to 50% more nucleic acid from cultured cells. Achieve yields of 3.5x or more for FFPE samples versus column-based methods.

No Beads, Columns, or Surface-binding: Nucleic acids are purified solely based on electrophoretic mobility. Elimination of binding, washing, and stripping reduces sample loss and contamination.

No Risk Downstream: Purification is not biased toward nucleic acids of a certain length or GC content.

Superior Workflow for FFPE: Purification of nucleic acids from FFPE scrolls or slides requires less than 3 minutes of hands-on time per sample (lysis included). No chemical deparaffinization is required.

Automated Nucleic Acid Purification: Nucleic acids are automatically separated and concentrated from sample lysate on the Purigen system in 60 minutes.

See the Purigen Technology in Action

The application of ITP to purify and quantify nucleic acids from complex biological samples was pioneered by Purigen co-founder and Stanford University Professor, Juan G. Santiago. The Ionic Purification System is compatible with a range of samples including cells and FFPE.

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PURIGEN FFPE Workflow

Total hands-on time is ~24 minutes per 8 samples

Purigen FFPE Workflow